Biostatistician with over three decades of pioneering work spanning experimental radioecology, mathematical modeling, and pharmaceutical regulation. Career progression from compartmental modeling research to establishing computational foundations for European drug regulation at the European Medicines Agency.
30+
Publications
100+
Conferences
32
Years Research
Education
PhD in Biostatistics - Medical Statistics
State University of Milan, Faculty of Medicine
Milan, Italy • 1975
Comprehensive Application of Compartmental Modelling to Biological and Medical Systems
Mathematical work focused on functional optimization for parameter estimation. Awarded maximum possible marking.
Supervisors: Prof. Alfredo Maccacaro (trained at Sir Ronald Fisher's school) and Dr. Giulio Di Cola (leading Italian numerical analyst)
MSci General Biology
State University of Milan, Science Faculty
Milan, Italy • 1970
Experimental Radioecology: Metabolism of Zinc-65 in Fresh Water Fish
Pioneering experimental work introducing compartmental modeling concepts. Awarded maximum possible marking.
Supervisors: Dr. Margaret Merlini (major US radioecologist) and Prof. Vittorio Capraro (Head of Physiology)
Technical Diploma in Industrial Chemistry
ITIP Technical Institute
Rovigo, Italy • 1963
Graduated with high honors, providing strong mathematical and chemical foundation.
Professional Experience
Head of European Commission Support Team
European Medicine Agency (EMA)
London, United Kingdom • 1997-2002
Led complete transition of ETOMEP operations to London, managing computational regulatory systems for the European Medicines Agency. Oversaw development of critical statistical computation infrastructure forming the backbone of European pharmaceutical regulation.
- Managed relocation and integration of 25-person technical team
- Developed computational regulatory systems still in use today
- Produced numerous regulatory publications and technical documentation
Head of European Technical Office for Medicinal Products (ETOMEP)
European Commission Joint Research Centre
Ispra, Italy • 1990-1997
Established and led ETOMEP with 25 staff as primary statistical computation support for the emerging European Medicine Evaluation Agency. Pioneered development of computational systems for pharmaceutical regulation in Europe.
- Built ETOMEP as formal unit in Commission organizational structure
- Managed transition from Brussels proto-agency to London headquarters
- Established foundational regulatory computational protocols
Senior Scientific Officer - Applied Statistics
European Commission Joint Research Centre
Ispra, Italy • 1981-1990
Led team of 10 staff in fissile material management statistical accountancy, serving as EC JRC partner for IAEA safeguarding of nuclear materials in the European Community.
- Developed statistical accountancy systems for nuclear material safeguards
- Produced significant research output and multiple publications
- Successfully completed European involvement with IAEA safeguards program
Research Fellow - Applied Statistics
University of Reading, Department of Applied Statistics
Reading, United Kingdom • 1972
Worked under Prof. Robert Curnow in collaboration with Dr. John Jones on compartmental analysis applied to sheep population dynamics in the UK.
- Applied compartmental modeling to population dynamics
- Produced significant publications from sheep population studies
Scientific Officer - Radioecology
Euratom, Biology Division
Ispra, Italy • 1970-1972
Conducted advanced research on zinc metabolism in freshwater fish, investigating cadmium inhibition effects and detailed distribution in fish organs. Team of 4 members under Dr. Margaret Merlini's leadership.
- Advanced research on zinc metabolic pathways and absorption mechanisms
- Co-authored significant publications in radioecology
- Developed foundational expertise in compartmental modeling
Languages
Italian
Native Speaker
English
Fluent
French
Intermediate